Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 148
interventional 93
Observational 52
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Dietary Supplement 16
Drug|placebo 16
Other 12
Dietary Supplement|placebo 10
Biological|placebo 7
Drug 6
Device 5
Behavioral 3
Biological 2
Dietary Supplement|Drug|placebo 2
Dietary Supplement|Other 2
Procedure 2
Behavioral|Device 1
Behavioral|Drug 1
Behavioral|Drug|placebo 1
Biological|Other 1
Biological|Other|placebo 1
Diagnostic Test 1
Diagnostic Test|Procedure 1
Dietary Supplement|Other|placebo 1
Drug|Other 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 28
Italy 10
Finland 8
NA 5
Australia 4
Canada 4
Norway 4
United States|Canada 4
Sweden 3
Argentina 2
Australia|New Zealand 2
France 2
India 2
Netherlands 2
United Kingdom 2
Belgium|Germany 1
Canada|United Kingdom 1
Czechia 1
Hong Kong 1
Hungary 1
Poland 1
Romania 1
Spain 1
United States|Australia|New Zealand 1
United States|Canada|Spain 1
United States|Finland|France|Netherlands|Spain 1

Sites per Study

Site_count Study_Count
1 64
2 10
3 4
4 4
6 1
7 2
9 2
15 1
23 1
33 1
41 1
62 1
109 1

Phase

Phase Study_Count
N/A 47
Phase 2 18
Phase 1 13
Phase 1/Phase 2 5
Early Phase 1 3
Phase 2/Phase 3 3
Phase 4 3
Phase 3 1

Number of Arms

Number_of_Arms Count_of_Studies
1 17
2 50
3 12
4 5
5 1
6 2
7 2
9 1
14 1
25 1
NA 1

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 16.00000 3.000 5.00000 12 8.00000 33.0 630 20.0000
1st Qu. 28.00000 24.500 19.00000 14 44.25000 37.0 630 55.0000
Median 40.00000 45.000 28.00000 38 77.00000 41.0 630 90.0000
Mean 63.33333 1248.447 34.92308 34 91.61111 58.0 630 113.3333
3rd Qu. 87.00000 116.500 36.00000 40 116.25000 70.5 630 160.0000
Max. 134.00000 54000.000 136.00000 66 342.00000 100.0 630 230.0000

Trial Group Type

group_type Group_Count
Experimental 136
Placebo Comparator 50
Active Comparator 41
No Intervention 12
Other 11
Sham Comparator 2
NA 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 59
Single Group Assignment 19
Crossover Assignment 12
Sequential Assignment 3

Primary Purpose

primary_purpose Study_Count
Treatment 52
Diagnostic 17
Prevention 7
Supportive Care 6
Other 5
Basic Science 3
NA 2
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 17
United Kingdom 6
Italy 4
NA 4
Finland 3
Israel 3
Canada 2
Spain 2
Argentina 1
Australia 1
Denmark 1
Finland|Romania 1
France 1
Norway 1
Sweden 1
Turkey 1
United States|Canada 1
United States|Finland|Italy 1
United States|Italy 1

Sites per Study

Site_count Study_Count
1 42
2 6
5 1
6 1
10 1
13 1

Enrollment Metrics

Measure Observational
Min 5.000
1st Qu 50.000
Median 100.000
Mean 3356.942
3rd Qu 500.000
Max 120000.000

Observation Model

observational_model Study_Count
Cohort 20
Case-Control 11
Case-Only 8
Other 4
NA 4
Case Control 3
Case Control, Natural History 1
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 34
Cross-Sectional 10
Retrospective 4
NA 2
Longitudinal, Prospective 1
Other 1

Registries

Studies by Country

Country Study_Count
Italy 1
Russian Federation 1
Turkey 1

Sites per Study

Site_count Study_Count
1 3

Enrollment Metrics

Measure Registries
Min 37.000
1st Qu 45.000
Median 53.000
Mean 1053.333
3rd Qu 1561.500
Max 3070.000

Registry Model

observational_model Study_Count
Case-Control 2
Other 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 2
Prospective 1

Follow-up

target_duration Study_Count
28 Days 1
3 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03775499 Probiotic BL NCC 2705 and Gluten Sensitivity https://ClinicalTrials.gov/show/NCT03775499 Active, not recruiting Nestlé 2019-10-04
NCT03409796 Assessment of Immune Activation and Tolerance in Celiac Disease https://ClinicalTrials.gov/show/NCT03409796 Completed Takeda 2019-05-02
NCT03380988 Fiber-enriched Buckwheat Pasta and Glucose Variability in Patients With Type 1 Diabetes and Celiac Disease https://ClinicalTrials.gov/show/NCT03380988 Completed Federico II University 2016-12-31
NCT03321214 Gluten Sensor Device to Promote Gluten Free Diet Adherence and Quality of Life in Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT03321214 Completed Columbia University 2018-10-31
NCT03288831 Changes in Intestinal Permeability 4 Hours After Gluten Challenge https://ClinicalTrials.gov/show/NCT03288831 Completed Mayo Clinic 2018-10-30
NCT03271138 Bifidobacterium Infantis NLS Super Strain for Celiac Disease Patients on a Gluten-free Diet With Persistent Gastrointestinal Symptoms https://ClinicalTrials.gov/show/NCT03271138 Completed Global Institute of Probiotics 2017-12-07
NCT03176095 Celiac Disease Prevention With Probiotics https://ClinicalTrials.gov/show/NCT03176095 Completed Lund University 2015-08-30
NCT03064997 Prebiotic as a Supplement of Gluten-free Diet in the Management of Celiac Disease in Children https://ClinicalTrials.gov/show/NCT03064997 Completed Polish Academy of Sciences 2016-03-01
NCT03037190 Preservation of Residual Beta Cell Mass and Prevention of Celiac Disease in Children With Recent Onset Type 1 Diabetes https://ClinicalTrials.gov/show/NCT03037190 Recruiting Lund University 2020-12-31
NCT03011931 Simvastatin Metabolism as a Test for CD Activity (IRB 15-007568] https://ClinicalTrials.gov/show/NCT03011931 Completed Immunogenics, LLC 2019-01-31
NCT03011593 Effect of UGIR in Adults With Compromised Gut Function and Malabsorption https://ClinicalTrials.gov/show/NCT03011593 Completed Metagenics, Inc. 2016-06-30
NCT02965209 European Novel Motorized Spiral Endoscopy Trial https://ClinicalTrials.gov/show/NCT02965209 Completed Evangelisches Krankenhaus Düsseldorf 2018-02-03
NCT02895438 Non Coeliac Gluten Sensitivity in Children https://ClinicalTrials.gov/show/NCT02895438 Completed Centre Hospitalier Universitaire de Saint Etienne 2017-10-04
NCT02764931 Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 1 https://ClinicalTrials.gov/show/NCT02764931 Recruiting University of Turku 2019-12-31
NCT02754609 Hookworm Therapy for Coeliac Disease https://ClinicalTrials.gov/show/NCT02754609 Completed James Cook University, Queensland, Australia 2019-10-31
NCT02711696 Randomized Clincal Trial on the Effect of a Restricted Gluten Contamination Elimination Diet Among Celiacs [GluCED] https://ClinicalTrials.gov/show/NCT02711696 Completed Università degli Studi di Brescia 2015-06-30
NCT02679014 A Study to Investigate the Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Repeated Dosing of RO5459072 in Volunteers With Celiac Disease https://ClinicalTrials.gov/show/NCT02679014 Completed Hoffmann-La Roche 2016-08-28
NCT02675283 Case Finding for Coeliac Disease Using a Point of Care Test in a Pharmacy Setting https://ClinicalTrials.gov/show/NCT02675283 Completed Sheffield Teaching Hospitals NHS Foundation Trust 2017-10-31
NCT02637141 A Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT02637141 Completed Amgen 2017-02-15
NCT02633020 Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease https://ClinicalTrials.gov/show/NCT02633020 Completed Amgen 2017-04-11
NCT02612766 Safety and Tolerability of Oat Containing Gluten-free Diet https://ClinicalTrials.gov/show/NCT02612766 Completed Alfred Rusescu Institute for Mother and Child Care 2016-12-31
NCT02528799 Safety and Tolerability of Nexvax2 in Subjects With Celiac Disease https://ClinicalTrials.gov/show/NCT02528799 Completed ImmusanT, Inc. 2017-01-06
NCT02472704 Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo https://ClinicalTrials.gov/show/NCT02472704 Completed Hospital Mutua de Terrassa 2014-04-30
NCT02458898 Text Message Intervention to Improve Adherence in Adolescents and Young Adults With Celiac Disease https://ClinicalTrials.gov/show/NCT02458898 Completed Stanford University 2016-05-31
NCT02344758 Gluten-free Diet Monitoring in Urine https://ClinicalTrials.gov/show/NCT02344758 Completed University of Seville 2013-07-31
NCT02244047 Cytokine Profile in Children With Celiac Disease https://ClinicalTrials.gov/show/NCT02244047 Completed University Medical Centre Maribor 2014-06-30
NCT02220166 Safety of Prolonged Administration of Triticum Monococcum in Celiac Disease https://ClinicalTrials.gov/show/NCT02220166 Completed Università degli Studi di Brescia 2011-07-31
NCT02202681 Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule https://ClinicalTrials.gov/show/NCT02202681 Recruiting Massachusetts General Hospital 2020-07-31
NCT01317914 Prospective Study of Undiagnosed Celiac Disease https://ClinicalTrials.gov/show/NCT01317914 Completed Mayo Clinic 2012-04-30
NCT01990885 Safety and Systemic Exposure Study of BL-7010 in Well-Controlled Celiac Patients. https://ClinicalTrials.gov/show/NCT01990885 Completed BioLineRx, Ltd. 2014-10-31
NCT03351972 Differences in Preparation for Small Bowel Capsule Endoscopy https://ClinicalTrials.gov/show/NCT03351972 Recruiting Sheffield Teaching Hospitals NHS Foundation Trust 2019-11-01
NCT01932476 Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes https://ClinicalTrials.gov/show/NCT01932476 Completed Joslin Diabetes Center 2014-12-31
NCT01893775 Antibody Treatment for Advanced Celiac Disease https://ClinicalTrials.gov/show/NCT01893775 Completed National Institutes of Health Clinical Center (CC) 2019-12-20
NCT01787825 Comparison of Capso Vision SV-1 to PillCam SB2 in the Evaluation of Subjects With Suspected Small Bowel Disease https://ClinicalTrials.gov/show/NCT01787825 Completed Capso Vision, Inc. 2015-04-30
NCT01765647 Oral AGY for Celiac Disease https://ClinicalTrials.gov/show/NCT01765647 Completed Igy Inc. 2015-08-31
NCT01762579 Bio-markers of Not-celiac Wheat Sensitivity https://ClinicalTrials.gov/show/NCT01762579 Recruiting University of Palermo 2016-01-01
NCT01762566 Bioelectrical Impedance Analysis of Not-celiac Wheat Sensitivity Patients https://ClinicalTrials.gov/show/NCT01762566 Completed University of Palermo 2013-10-31
NCT01695681 Screen-detected Coeliac Disease, a Population Based Study https://ClinicalTrials.gov/show/NCT01695681 Completed University Hospital of North Norway 2015-04-15
NCT01661933 Desensitising Celiac Disease Patients With the Human Hookworm https://ClinicalTrials.gov/show/NCT01661933 Completed The Prince Charles Hospital 2014-03-31
NCT01566110 Celiac Disease and Diabetes- Dietary Intervention and Evaluation Trial https://ClinicalTrials.gov/show/NCT01566110 Completed The Hospital for Sick Children 2018-03-31
NCT01558557 Gluten Free Diet in People With Schizophrenia: A Pilot Study https://ClinicalTrials.gov/show/NCT01558557 Completed University of Maryland, Baltimore 2014-01-31
NCT01439035 Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults https://ClinicalTrials.gov/show/NCT01439035 Completed Massachusetts General Hospital 2010-02-04
NCT01396213 A Double-blind Placebo-controlled Study to Evaluate Larazotide Acetate for the Treatment of Celiac Disease https://ClinicalTrials.gov/show/NCT01396213 Completed Innovate Biopharmaceuticals 2013-08-20
NCT01338324 Protocol for Correlating Enteropathic Severity and Small Intestinal CYP3A4 Activity in Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT01338324 Completed All India Institute of Medical Sciences, New Delhi 2011-06-30
NCT04248855 Evaluation of KAN-101 in Celiac Disease https://ClinicalTrials.gov/show/NCT04248855 Recruiting Anokion SA 2020-11-30
NCT04243551 Prospective, Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Symptomatic CD Patients https://ClinicalTrials.gov/show/NCT04243551 Recruiting Immunogenics, LLC 2021-06-30
NCT04160767 Celiac Disease and Vitamin Status: Evaluation of the Effect of Supplementation With a Probiotic (VIVOMIXX®) in a Cohoort of Celiac Patients https://ClinicalTrials.gov/show/NCT04160767 Recruiting University of Milan 2021-01-31
NCT04041622 Coeliac Disease in the Nord-Trøndelag Health Study (HUNT) https://ClinicalTrials.gov/show/NCT04041622 Recruiting Norwegian University of Science and Technology 2021-07-31
NCT04014660 Prevention av Autoimmunitet Med Laktobaciller https://ClinicalTrials.gov/show/NCT04014660 Recruiting Lund University 2021-12-31
NCT04014413 Safety and Efficacy of Fecal Microbiota Transplantation https://ClinicalTrials.gov/show/NCT04014413 Recruiting Chinese University of Hong Kong 2023-10-31
NCT03866538 Budesonide in Patients With Immune Mediated Enteropathies https://ClinicalTrials.gov/show/NCT03866538 Recruiting Mayo Clinic 2020-09-01
NCT03857360 Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease https://ClinicalTrials.gov/show/NCT03857360 Recruiting Università Politecnica delle Marche 2021-03-15
NCT03763487 The Aim of This Project is to Verify Whether a Depletion of B Cell Memory Subpopulation (“Marginal-zone-like”) CD19 + IgD + CD27 + and CD19 + IgM + CD27 + is a Useful Indicator of Hyposplenism in Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT03763487 Recruiting University Hospital Hradec Kralove 2018-12-31
NCT03707730 A Randomized, Double-Blind, Placebo Controlled, Crossover Trial to Evaluate Safety and Efficacy of AGY in Celiac Disease https://ClinicalTrials.gov/show/NCT03707730 Recruiting Igy Inc. 2022-12-31
NCT03701555 Assess the Safety, Tolerability, Pharmacokinetics (PK), and Gluten Degradation Activity of PvP001, PvP002, and PvP003 in Healthy Adult Volunteers and to Assess the Safety, Tolerability, and PK of PvP001 and PvP002 in Adults With Celiac Disease (CeD) https://ClinicalTrials.gov/show/NCT03701555 Recruiting Takeda 2020-08-31
NCT03678935 Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients https://ClinicalTrials.gov/show/NCT03678935 Active, not recruiting Oslo University Hospital 2019-06-01
NCT03644602 Low FODMAPs Diet in Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT03644602 Completed Federico II University 2016-12-31
NCT03644069 A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD) https://ClinicalTrials.gov/show/NCT03644069 Active, not recruiting ImmusanT, Inc. 2019-09-30
NCT03585478 Latiglutenase as a Treatment for Celiac Disease https://ClinicalTrials.gov/show/NCT03585478 Recruiting Immunogenics, LLC 2020-02-29
NCT03543540 Bioequivalence Study of Nexvax2 in Subjects With Celiac Disease https://ClinicalTrials.gov/show/NCT03543540 Completed ImmusanT, Inc. 2018-09-10
NCT03520244 A 12-week Exercise Program for Adults With Celiac Disease https://ClinicalTrials.gov/show/NCT03520244 Completed University of Calgary 2018-03-30
NCT03486990 Study of the Safety, Tolerability and Pharmacokinetics of TIMP-GLIA in Subjects With Celiac Disease https://ClinicalTrials.gov/show/NCT03486990 Completed Takeda 2019-05-24
NCT03483805 Effects of a Nutritional Solution to Improve Intestinal Permeability in Celiac Patients https://ClinicalTrials.gov/show/NCT03483805 Completed Société Guaranteed Gluten Free (GGF) 2018-01-12
NCT03462979 Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease https://ClinicalTrials.gov/show/NCT03462979 Recruiting Boston Children’s Hospital 2021-12-31
NCT01257620 Clinical Trial on the Effects of Bifidobacterium Infantis in Active Celiac Disease https://ClinicalTrials.gov/show/NCT01257620 Completed Bai, Julio M.D. 2011-09-30
NCT01255696 Safety and Efficacy of Varying Methods of ALV003 Administration for the Treatment of Celiac Disease https://ClinicalTrials.gov/show/NCT01255696 Completed Alvine Pharmaceuticals Inc. 2011-05-31
NCT01137955 Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT01137955 Completed Columbia University 2008-04-30
NCT01116505 Treatment of Screen-detected Celiac Disease https://ClinicalTrials.gov/show/NCT01116505 Completed Tampere University Hospital 2012-07-31
NCT01100099 HLA-DQ2-gliadin Tetramer for Diagnosis of Celiac Disease https://ClinicalTrials.gov/show/NCT01100099 Completed Oslo University Hospital 2009-12-31
NCT01094041 Gluten Intolerance in Patients With Diarrhea Predominant Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT01094041 Completed Mayo Clinic 2012-01-31
NCT01045837 Effect of Addition of Short Course of Prednisolone to Gluten Free Diet in Naive Celiac Disease Patients https://ClinicalTrials.gov/show/NCT01045837 Completed All India Institute of Medical Sciences, New Delhi 2010-04-30
NCT00962182 Study of Enzyme Supplements to Treat Celiac Disease https://ClinicalTrials.gov/show/NCT00962182 Completed Heim Pal Children’s Hospital 2014-12-31
NCT00959114 Safety and Efficacy of ALV003 for the Treatment of Celiac Disease https://ClinicalTrials.gov/show/NCT00959114 Completed Alvine Pharmaceuticals Inc. 2010-08-31
NCT00931892 Serum Markers in Gluten Challenge https://ClinicalTrials.gov/show/NCT00931892 Completed Beth Israel Deaconess Medical Center 2011-08-31
NCT00889473 Study of the Efficacy of Larazotide Acetate to Treat Celiac Disease https://ClinicalTrials.gov/show/NCT00889473 Completed Innovate Biopharmaceuticals 2009-11-30
NCT00879749 Safety Study of Nexvax2 in Subjects With Coeliac Disease https://ClinicalTrials.gov/show/NCT00879749 Completed Nexpep Pty Ltd 2010-03-31
NCT03738475 Study of the Safety, Pharmacodynamics, Efficacy, and PK of TIMP-GLIA in Subjects With Celiac Disease https://ClinicalTrials.gov/show/NCT03738475 Active, not recruiting COUR Pharmaceutical Development Company, Inc. 2019-07-31
NCT02389062 Noninvasive Markers of Gluten Ingestion in Celiac Disease Patients https://ClinicalTrials.gov/show/NCT02389062 Completed Thomas Jefferson University 2016-02-11
NCT00810654 Effect of Aspergillus Niger Prolyl Endoprotease (AN-PEP) Enzyme on the Effects of Gluten Ingestion in Patients With Coeliac Disease https://ClinicalTrials.gov/show/NCT00810654 Completed VU University Medical Center 2009-05-31
NCT03137862 “Gluten Friendly” Treatment in Celiac Disease https://ClinicalTrials.gov/show/NCT03137862 Completed Casa Sollievo della Sofferenza IRCCS 2017-04-02
NCT03562221 Prevention of Celiac Disease in Skåne https://ClinicalTrials.gov/show/NCT03562221 Recruiting Lund University 2024-08-31
NCT03569007 Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms https://ClinicalTrials.gov/show/NCT03569007 Recruiting Innovate Biopharmaceuticals 2021-08-31
NCT00677495 Gluten-free Diet in Gluten-genetically Predisposed Subjects https://ClinicalTrials.gov/show/NCT00677495 Active, not recruiting IRCCS Burlo Garofolo 2019-12-31
NCT00671138 Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity https://ClinicalTrials.gov/show/NCT00671138 Completed Princess Alexandra Hospital, Brisbane, Australia 2008-12-31
NCT00669825 Study of ALV003 in Healthy Adult Volunteers and Subjects With Well-Controlled Celiac Disease Following a Gluten-Containing Meal https://ClinicalTrials.gov/show/NCT00669825 Completed Alvine Pharmaceuticals Inc. 2008-10-31
NCT00639444 Risk of Celiac Disease and Age at Gluten Introduction https://ClinicalTrials.gov/show/NCT00639444 Completed Università Politecnica delle Marche 2007-12-31
NCT00628823 Treatment of Mild Enteropathy Celiac Disease https://ClinicalTrials.gov/show/NCT00628823 Completed Tampere University Hospital 2008-06-30
NCT00626184 A Phase 1, Study of the Safety and Tolerability of ALV003 in Healthy Adult Volunteers and Subjects With Well-Controlled Celiac Disease https://ClinicalTrials.gov/show/NCT00626184 Completed Alvine Pharmaceuticals Inc. 2008-05-31
NCT00620451 Randomized, Double-Blind, Placebo-Controlled Study of Larazotide Acetate in Subjects With Active Celiac Disease https://ClinicalTrials.gov/show/NCT00620451 Completed Innovate Biopharmaceuticals 2009-07-31
NCT00540657 A Phase II Study of CCX282-B in Patients With Celiac Disease https://ClinicalTrials.gov/show/NCT00540657 Completed ChemoCentryx 2008-06-30
NCT00492960 Study to Assess the Efficacy of Larazotide Acetate for the Treatment of Celiac Disease https://ClinicalTrials.gov/show/NCT00492960 Completed Innovate Biopharmaceuticals 2008-10-31
NCT00386165 Safety Study of Larazotide Acetate to Treat Celiac Disease. https://ClinicalTrials.gov/show/NCT00386165 Completed Innovate Biopharmaceuticals 2006-01-26
NCT00362856 Safety and Tolerability Study of Larazotide Acetate in Celiac Disease Subjects https://ClinicalTrials.gov/show/NCT00362856 Completed Innovate Biopharmaceuticals 2007-03-06

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03364556 Nutritional Intake and Bone Health in Celiac Disease https://ClinicalTrials.gov/show/NCT03364556 Completed George Mason University 2017-11-30
NCT03320811 Interpretation of Serological Tests in the Diagnosis of Celiac Disease: Anti-deamidated Gliadin Peptide Antibodies Revisited https://ClinicalTrials.gov/show/NCT03320811 Completed CHU de Reims 2015-09-01
NCT03152279 Assessment of Duodenal Epithelial Integrity in Celiac Disease With Mucosal Impedance https://ClinicalTrials.gov/show/NCT03152279 Completed Vanderbilt University Medical Center 2018-11-07
NCT03143517 Fecal Calprotectin Collection Protocol https://ClinicalTrials.gov/show/NCT03143517 Completed DiaSorin Inc. 2018-08-23
NCT03136731 Evidence-based Screening Strategies for Celiac Disease https://ClinicalTrials.gov/show/NCT03136731 Enrolling by invitation Tampere University Hospital 2022-12-31
NCT03122093 Celiac Disease and Diabetes Longitudinal Follow-up and Evaluation Study https://ClinicalTrials.gov/show/NCT03122093 Active, not recruiting The Hospital for Sick Children 2020-05-31
NCT02834429 Pre-endoscopy Serological Testing for Coeliac Disease; a Novel Approach Using Rapid Antibody Testing https://ClinicalTrials.gov/show/NCT02834429 Completed Sheffield Teaching Hospitals NHS Foundation Trust 2017-08-31
NCT02805816 Choosing a Preferred Serology Kit for Screening and Diagnosis of Celiac Disease https://ClinicalTrials.gov/show/NCT02805816 Completed Rabin Medical Center 2017-06-30
NCT02761785 Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 2 https://ClinicalTrials.gov/show/NCT02761785 Completed University of Turku 2018-05-15
NCT02711397 Quantification of Gluten Peptides in Feces https://ClinicalTrials.gov/show/NCT02711397 Completed Biomedal S.L. 2014-06-30
NCT02690532 Gut Permeability Assessment in Celiac and Gluten Sensitive Children https://ClinicalTrials.gov/show/NCT02690532 Completed Mayo Clinic 2018-07-01
NCT02551289 MAgnetic Resonance Imaging in COeliac Disease https://ClinicalTrials.gov/show/NCT02551289 Completed University of Nottingham 2018-10-19
NCT02451449 Celiac Disease and Infertility Among Men and Women in Denmark https://ClinicalTrials.gov/show/NCT02451449 Completed University of Aarhus 2017-09-30
NCT02442219 A Blood Based Diagnostic Test for Coeliac Disease https://ClinicalTrials.gov/show/NCT02442219 Recruiting Oslo University Hospital 2021-11-27
NCT02312349 Assessment of Gluten-Free Availability in Elaborated Food Stores in Three Neighbourhoods of Buenos Aires City https://ClinicalTrials.gov/show/NCT02312349 Completed Hospital Italiano de Buenos Aires 2013-01-31
NCT02242123 Celiac Disease Diagnosis in Patients With Weakly Positive Serum Anti-Transglutaminase: Duodenal Anti-Endomysium Assay. https://ClinicalTrials.gov/show/NCT02242123 Recruiting University of Palermo 2016-12-31
NCT02203201 Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS) https://ClinicalTrials.gov/show/NCT02203201 Recruiting University of Palermo 2016-10-01
NCT02072590 Improved Diagnostics of Celiac Disease in Children https://ClinicalTrials.gov/show/NCT02072590 Recruiting Tampere University Hospital 2022-12-31
NCT02061306 Celiac Disease Genomic Environmental Microbiome and Metabolomic Study https://ClinicalTrials.gov/show/NCT02061306 Recruiting Massachusetts General Hospital 2024-12-31
NCT01931644 At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions https://ClinicalTrials.gov/show/NCT01931644 Recruiting Sanguine Biosciences 2025-08-31
NCT01909050 Immune Response in Celiac Disease on In-vitro Gluten Challenge https://ClinicalTrials.gov/show/NCT01909050 Completed Beth Israel Deaconess Medical Center 2018-01-31
NCT01862510 Detection of Celiac Disease in Patients With Hypothyroidism https://ClinicalTrials.gov/show/NCT01862510 Completed University of Vermont 2014-12-31
NCT01813383 Clinical Relevance of Typing HLA-DR7-DQ2 https://ClinicalTrials.gov/show/NCT01813383 Completed Corporacion Parc Tauli 2012-12-31
NCT01574209 Gut Peptides and Intestinal Permeability in Celiac Disease and Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT01574209 Completed Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 2012-09-30
NCT01560169 Evaluation of Patient Reported Outcome Instruments in Celiac Disease Patients https://ClinicalTrials.gov/show/NCT01560169 Completed Alvine Pharmaceuticals Inc. 2013-09-30
NCT01558570 Intracellular Tight Junction Permeability in Schizophrenia: Focus on Zonulin https://ClinicalTrials.gov/show/NCT01558570 Completed University of Maryland, Baltimore 2012-02-29
NCT01478867 Detection of Immunotoxic Gluten Peptides in Feces https://ClinicalTrials.gov/show/NCT01478867 Completed University of Seville NA
NCT01476995 Prognostic Indicators as Provided by the EPIC ClearView https://ClinicalTrials.gov/show/NCT01476995 Completed Epic Research & Diagnostics, Inc. 2011-06-30
NCT04351828 Intestinal Permeability, Nutritional Status and Quality of Life in Celiac Disease https://ClinicalTrials.gov/show/NCT04351828 Completed Marmara University 2019-04-11
NCT04349904 Near-Focus NBI Classification of Villous Atrophy in Suspected Coeliac Disease: International Development and Validation https://ClinicalTrials.gov/show/NCT04349904 Completed King’s College Hospital NHS Trust 2018-07-26
NCT03521180 A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease https://ClinicalTrials.gov/show/NCT03521180 Completed Celgene 2019-07-18
NCT04306939 Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study https://ClinicalTrials.gov/show/NCT04306939 Recruiting University of Pittsburgh 2025-12-01
NCT04240340 Experiences of Disclosure in Adolescents With Coeliac Disease https://ClinicalTrials.gov/show/NCT04240340 Recruiting University of Oxford 2020-06-30
NCT04148235 A Pilot Study to Explore the Role of Gut Flora in Celiac Disease https://ClinicalTrials.gov/show/NCT04148235 Recruiting ProgenaBiome 2023-03-31
NCT04034303 Risk Factors for the Development of Celiac Disease in Genetically Predisposed Children https://ClinicalTrials.gov/show/NCT04034303 Enrolling by invitation Federico II University 2022-05-01
NCT04012736 Physical Fitness in Celiac Disease Patients - the Effect of a Gluten Free Diet https://ClinicalTrials.gov/show/NCT04012736 Active, not recruiting Meir Medical Center 2020-07-01
NCT03966625 Serological Identification of Celiac Disease in Kids https://ClinicalTrials.gov/show/NCT03966625 Recruiting Sahlgrenska University Hospital, Sweden 2021-07-31
NCT03941184 Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity https://ClinicalTrials.gov/show/NCT03941184 Recruiting Mayo Clinic 2020-12-31
NCT03663309 Assessment of Adherence to Gluten Free Diet in Children and Adolescents by Detection of Gluten in Faecal Samples. https://ClinicalTrials.gov/show/NCT03663309 Recruiting Rabin Medical Center 2020-09-30
NCT03434639 Fluorescence Spectroscopy for Gut Permeability Assessment https://ClinicalTrials.gov/show/NCT03434639 Recruiting Imperial College London 2021-09-30
NCT01172665 Celiac Disease Database https://ClinicalTrials.gov/show/NCT01172665 Recruiting University of Chicago 2025-09-30
NCT01145287 Impact of the Diagnosis of Celiac Disease https://ClinicalTrials.gov/show/NCT01145287 Completed Tampere University Hospital 2016-04-30
NCT01129908 Saliva Composition and Oral Hygiene in Children With Celiac Disease Before and After the Change in Diet https://ClinicalTrials.gov/show/NCT01129908 Completed Hadassah Medical Organization 2012-07-31
NCT01010360 Identification of Celiac Ganglia https://ClinicalTrials.gov/show/NCT01010360 Completed Indiana University 2012-09-30
NCT00859391 Effects of Gluten Digestion With ALV003 https://ClinicalTrials.gov/show/NCT00859391 Completed Alvine Pharmaceuticals Inc. 2008-06-30
NCT02190513 Prevalence of Eosinophilic Esophagitis in Children With Celiac Disease https://ClinicalTrials.gov/show/NCT02190513 Completed St. John Health System, Michigan 2013-06-30
NCT00782366 Predictive Genetic Risk Assessment Trial https://ClinicalTrials.gov/show/NCT00782366 Completed Mayo Clinic 2010-01-31
NCT00692861 Autoimmunity in Neurologic Complications of Celiac Disease https://ClinicalTrials.gov/show/NCT00692861 Completed National Institutes of Health Clinical Center (CC) NA
NCT00555737 Performance Evaluation of Capsule Endoscopy in the Diagnosis of Gluten Sensitive Enteropathy (MA-23) https://ClinicalTrials.gov/show/NCT00555737 Completed Medtronic - MITG NA
NCT00175760 Can a Very High Result From a Screening Test for Celiac Disease be Used to Diagnose Celiac Disease? https://ClinicalTrials.gov/show/NCT00175760 Completed University of British Columbia 2006-10-31
NCT00138879 Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn’s Disease Patients https://ClinicalTrials.gov/show/NCT00138879 Completed St Mark’s Hospital Foundation NA
NCT00006492 Gluten-Free Diet in Patients With Gluten Sensitivity and Cerebellar Ataxia https://ClinicalTrials.gov/show/NCT00006492 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03221647 INF-α Innate Immune Response to Gliadin https://ClinicalTrials.gov/show/NCT03221647 Completed Federico II University 2017-07-01
NCT04272983 Population Study of the Prevalence of Celiac Disease and Other Gluten-dependent Disorders in Children and Adolescents https://ClinicalTrials.gov/show/NCT04272983 Recruiting I.M. Sechenov First Moscow State Medical University 2020-12-31
NCT04024449 Can Celiac Disease Affect Ovarian Function in Adolescent? https://ClinicalTrials.gov/show/NCT04024449 Completed Bakirkoy Dr. Sadi Konuk Research and Training Hospital 2018-01-01